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Kuniaki Saito Selected Research

Kynurenine 3-Monooxygenase (Kynurenine 3 Monooxygenase)

11/2021Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity.
1/20213-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice.
3/2020Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.
1/2017Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice.

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Kuniaki Saito Research Topics

Disease

20Neoplasms (Cancer)
06/2022 - 03/2008
13Infections
11/2021 - 01/2003
13Inflammation (Inflammations)
08/2020 - 01/2002
10Glioma (Gliomas)
05/2021 - 03/2008
6Lymphoma (Lymphomas)
11/2021 - 05/2008
6Glioblastoma (Glioblastoma Multiforme)
01/2021 - 03/2008
5Carcinogenesis
11/2021 - 03/2010
4COVID-19
01/2022 - 09/2020
4Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
11/2021 - 04/2010
4Ischemia
03/2009 - 06/2005
3Shock
01/2021 - 01/2012
3Major Depressive Disorder (Major Depressive Disorders)
01/2021 - 01/2020
3Colitis
03/2020 - 09/2005
3Oligodendroglioma
01/2019 - 03/2008
3Cognitive Dysfunction
02/2017 - 05/2008
3Brain Neoplasms (Brain Tumor)
01/2017 - 01/2008
3Fibrosis (Cirrhosis)
01/2016 - 01/2013
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2016 - 05/2015
3Hepatitis
09/2014 - 02/2009
3Brain Ischemia (Cerebral Ischemia)
03/2009 - 06/2005
3Atherosclerosis
05/2005 - 04/2003
2Lewis Lung Carcinoma
06/2022 - 10/2019
2Seizures (Absence Seizure)
02/2022 - 04/2012
2Neurodevelopmental Disorders
02/2022 - 09/2019
2Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 11/2021
2Hepatocellular Carcinoma (Hepatoma)
11/2021 - 01/2016
2Chronic Hepatitis C
11/2021 - 01/2016
2Sepsis (Septicemia)
01/2021 - 11/2014
2Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2021 - 09/2019
2Autism Spectrum Disorder
02/2020 - 09/2019
2Mania (Manias)
02/2020 - 01/2020
2Schizophrenia (Dementia Praecox)
01/2019 - 01/2019
2Carcinoma (Carcinomatosis)
05/2018 - 10/2010
2Body Weight (Weight, Body)
06/2017 - 06/2013
2Myocarditis (Carditis)
01/2017 - 04/2012
2Liver Cirrhosis (Hepatic Cirrhosis)
01/2016 - 03/2005
2Viral Encephalitis
04/2015 - 04/2014
2Virus Diseases (Viral Diseases)
04/2015 - 01/2013
2Massive Hepatic Necrosis
09/2014 - 01/2009
2Neurodegenerative Diseases (Neurodegenerative Disease)
12/2010 - 03/2006
2Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
08/2009 - 01/2009

Drug/Important Bio-Agent (IBA)

23Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
03/2021 - 02/2008
22Tryptophan (L-Tryptophan)FDA Link
03/2021 - 02/2002
21CytokinesIBA
01/2022 - 04/2003
20Messenger RNA (mRNA)IBA
11/2021 - 01/2003
20KynurenineIBA
03/2021 - 02/2002
15EnzymesIBA
11/2021 - 01/2003
12Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2010 - 04/2002
10Proteins (Proteins, Gene)FDA Link
03/2020 - 01/2006
7Biomarkers (Surrogate Marker)IBA
11/2021 - 06/2013
6ProgranulinsIBA
11/2021 - 10/2014
5Biological ProductsIBA
11/2021 - 10/2018
5Interleukin-6 (Interleukin 6)IBA
01/2021 - 01/2006
4Immunoglobulin G (IgG)IBA
01/2022 - 09/2020
4Glycoproteins (Glycoprotein)IBA
11/2021 - 10/2014
4Kynurenine 3-Monooxygenase (Kynurenine 3 Monooxygenase)IBA
11/2021 - 01/2017
4LipopolysaccharidesIBA
01/2021 - 02/2003
4InterferonsIBA
10/2019 - 02/2004
4ChemokinesIBA
01/2017 - 03/2010
4Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
10/2014 - 03/2005
3AntigensIBA
01/2021 - 10/2004
33-hydroxykynurenineIBA
01/2021 - 12/2010
3Vincristine (Oncovin)FDA LinkGeneric
09/2020 - 04/2011
3Rituximab (Mabthera)FDA Link
09/2020 - 04/2010
3AntibodiesIBA
09/2020 - 03/2010
3Interleukin-10 (Interleukin 10)IBA
03/2020 - 09/2013
3sym-trinitrobenzeneIBA
03/2020 - 09/2005
3RNA (Ribonucleic Acid)IBA
01/2019 - 10/2004
3Doxorubicin (Adriamycin)FDA LinkGeneric
12/2017 - 04/2011
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2017 - 04/2011
3LipidsIBA
06/2017 - 01/2004
3NF-kappa B (NF-kB)IBA
09/2005 - 03/2005
2Glutamic Acid (Glutamate)FDA Link
02/2022 - 07/2007
2VaccinesIBA
01/2022 - 11/2021
2BNT162 VaccineIBA
01/2022 - 11/2021
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2021 - 01/2021
2Tryptophan Oxygenase (Tryptophan 2,3 Dioxygenase)IBA
03/2021 - 10/2019
2fosfestrol (Kyorin)FDA Link
01/2021 - 09/2020
2Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2021 - 03/2012
2Methotrexate (Mexate)FDA LinkGeneric
09/2020 - 05/2008
2Imiquimod (Aldara)FDA LinkGeneric
08/2020 - 04/2015
2Interleukin-17 (Interleukin 17)IBA
08/2020 - 01/2019
2Sulfates (Sulfates, Inorganic)IBA
03/2020 - 09/2013
2LithiumIBA
02/2020 - 01/2020
2Dextroamphetamine (Dexedrine)FDA LinkGeneric
02/2020 - 01/2020
2Kynurenic Acid (Kynurenate)IBA
01/2020 - 01/2019
2Pharmaceutical PreparationsIBA
10/2019 - 03/2008
2Serotonin (5 Hydroxytryptamine)IBA
01/2019 - 10/2011
21-methyltryptophanIBA
08/2015 - 09/2013
2Temozolomide (Temodar)FDA LinkGeneric
01/2014 - 03/2008
2Surface Antigens (Surface Antigen)IBA
08/2012 - 01/2003
2InterleukinsIBA
04/2012 - 01/2006
2Quinolinic AcidIBA
12/2010 - 07/2007
2Type I Tumor Necrosis Factor ReceptorsIBA
03/2010 - 03/2005
2CholesterolIBA
01/2009 - 05/2005

Therapy/Procedure

11Therapeutics
06/2022 - 03/2008
7Drug Therapy (Chemotherapy)
11/2021 - 05/2008
5Radiotherapy
01/2017 - 03/2008
3Aftercare (After-Treatment)
06/2022 - 10/2010
3Craniotomy
05/2021 - 02/2009